교수소개
교수
2004.02.26 서울대학교 (공학박사)
1999.02.26 서울대학교 (공학석사)
1997.02.26 서울대학교 (공학사)
2021.04 인천대학교 (교수)
2018.09 ~ 2019.08 Rice University (방문 교수)
2016.04 ~ 2021.03 인천대학교 (부교수)
2012.03 ~ 2016.03 인천대학교 (조교수)
2010.02 ~ 2012.03 LG생명과학 (차장)
2010.02 ~ 2012.03 LG 생명과학 (Senior Researcher)
2005.10 ~ 2010.02 Georgia Institute of Technology (Visiting Researcher)
2004.06 ~ 2005.10 서울대학교 공학연구소 (객원연구원)
2004.03 ~ 2004.05 서울대학교 공학연구소 (박사후과정, 보조연구원)
엑소좀 기반 염증성 장질환 치료제, Journal of Digestive Cancer Research , 제13권(집) , 제1호 , PP.1~8 , 2025.04.20
Plant-Derived Extracellular Vesicles: Current Status and Challenges for Developing a New Paradigm in Therapeutics Development, VIEW , 제6권(집) , 제1호 , PP.20240115~ , 2025.02.26
Exosomal miR-6126 as a novel therapeutic target for overcoming resistance of anti-cancer effect in hepatocellular carcinoma, BMC CANCER , 제24권(집) , 제1호 , 2024.12.20
Safe and efficient treatment of drug-resistant colorectal cancer cells using kaempferol-loaded exosomes, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제29권(집) , 제6호 , PP.1108~1117 , 2024.12.01
Advanced Enrichment and Separation of Extracellular Vesicles through the Super Absorbent Polymer Nanosieves, ACS Applied Materials & Interfaces , 제16권(집) , 제48호 , PP.65863~65876 , 2024.11.19
Exploiting Spinach-Derived Extracellular Vesicles for Anti-Obesity Therapy Through Lipid Accumulation Inhibition, Advanced Therapeutics , 제7권(집) , 제11호 , 2024.11.12
Engineered plant-derived extracellular vesicles for targeted regulation and treatment of colitis-associated inflammation, Theranostics , 제14권(집) , 제14호 , PP.5643~5661 , 2024.09.04
Perilla-Leaf-Derived Extracellular Vesicles Selectively Inhibit Breast Cancer Cell Proliferation and Invasion, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 제24권(집) , 제21호 , 2023.11.01
In situ simultaneous detection of surface protein and microRNA in clustered extracellular vesicles from breast cell lines using flow cytometry, ACS Biomaterials Science & Engineering , 제9권(집) , 제11호 , 2023.10.31
Bioreducible exosomes encapsulating glycolysis inhibitors potentiate mitochondria-targeted sonodynamic cancer therapy via cancer-targeted drug release and cellular energy depletion, BIOMATERIALS , 제301권(집) , 2023.10.01
Exosome membrane-sheathed and multi-stimuli-responsive MnO2 nanoparticles with self-oxygenation and energy depletion abilities potentiate the sonodynamic therapy of hypoxic tumors, Chemical Engineering Journal , 제472권(집) , 2023.09.15
Brain endothelial cell-derived extracellular vesicles with a mitochondria-targeting photosensitizer effectively treat glioblastoma by hijacking the blood‒brain barrier, Acta Pharmaceutica Sinica B , 제13권(집) , 제9호 , PP.3834~3848 , 2023.09.01
Mitochondria-targeting sonosensitizer-loaded extracellular vesicles for chemo-sonodynamic therapy, JOURNAL OF CONTROLLED RELEASE , 제354권(집) , PP.651~663 , 2023.02.01
Target-Responsive Template Structure Switching-Mediated Exponential Rolling Circle Amplification for the Direct and Sensitive Detection of MicroRNA, BioChip Journal , 제16권(집) , 제4호 , PP.422~432 , 2022.12.01
Suppression of inflammatory responses in macrophages by onion-derived extracellular vesicles, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY , 제115권(집) , PP.287~297 , 2022.11.25
Genomic and physiological analysis of C50 carotenoid-producing novel Halorubrum ruber sp. nov., JOURNAL OF MICROBIOLOGY , 제60권(집) , 제10호 , PP.1007~1020 , 2022.10.01
Size-selective filtration of extracellular vesicles with movable-layer device, LAB ON A CHIP , 제22권(집) , 제19호 , PP.3699~3707 , 2022.09.27
Isolation and characterization of urinary extracellular vesicles from healthy donors and patients with castration-resistant prostate cancer, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 제23권(집) , 제13호 , 2022.07.01
Extracellular vesicles with high dual drug loading for safe and efficient combination chemo-phototherapy, Biomaterials Science , 제10권(집) , 제11호 , PP.2817~2830 , 2022.05.31
Engineered extracellular vesicle-based sonotheranostics for dual stimuli-sensitive drug release and photoacoustic imaging-guided chemo-sonodynamic cancer therapy, Theranostics , 제12권(집) , 제3호 , PP.1247~1266 , 2022.01.01
Isolation of cabbage exosome-like nanovesicles and investigation of their biological activities in human cells, Bioactive Materials , 제6권(집) , 제12호 , PP.4321~4332 , 2021.12.01
Inhibition of tumor progression and M2 microglial polarization by extracellular vesicle-mediated microRNA-124 in a 3D microfluidic glioblastoma microenvironment, Theranostics , 제11권(집) , 제19호 , PP.9687~9704 , 2021.09.27
Antioxidative Effects of Carrot-Derived Nanovesicles in Cardiomyoblast and Neuroblastoma Cells, Pharmaceutics , 제13권(집) , 제8호 , 2021.08.05
Safe and Targeted Sonodynamic Cancer Therapy Using Biocompatible Exosome-Based Nanosonosensitizers, ACS Applied Materials & Interfaces , 제13권(집) , 제22호 , PP.25575~25588 , 2021.06.09
Phenylboronic Acid-conjugated Exosomes for Enhanced Anticancer Therapeutic Effect by Increasing Doxorubicin Loading Efficiency, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제26권(집) , 제1호 , PP.78~85 , 2021.02.28
Single-step equipment-free extracellular vesicle concentration using super absorbent polymer beads, Journal of Extracellular Vesicles , 제10권(집) , 제4호 , 2021.02.23
Single Step In Situ Detection of Surface Protein and MicroRNA in Clustered Extracellular Vesicles Using Flow Cytometry, Journal of Clinical Medicine , 제10권(집) , PP.319~ , 2021.01.17
Cell death in culture: Molecular mechanisms, detections, and inhibition strategies, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY , 제91권(집) , PP.37~53 , 2020.11.25
Exosome-mediated Let7c-5p Delivery for Breast Cancer Therapeutic Development, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제25권(집) , 제4호 , PP.513~520 , 2020.08.30
Vascular smooth muscle cell-derived exosomal miRNAs regulate endothelial cell migration under PDGF stimulation, Cells , 제9권(집) , 제3호 , 2020.03.06
Exosome-mediated microRNA-497 delivery for anti-cancer therapy in a microfluidic 3D lung cancer model, LAB ON A CHIP , 제20권(집) , 제3호 , PP.548~557 , 2020.02.07
The profiles of microRNAs from urinary extracellular vesicles (EVs) prepared by various isolation methods and their correlation with serum EV microRNAs, DIABETES RESEARCH AND CLINICAL PRACTICE , 제160권(집) , 2020.02.01
Development and comparative analysis of human urine exosome isolation strategies, PROCESS BIOCHEMISTRY , 제88권(집) , PP.197~203 , 2020.01.01
Simultaneous multiplexed detection of exosomal microRNAs and surface proteins for prostate cancer diagnosis, BIOSENSORS & BIOELECTRONICS , 제146권(집) , PP.111749~ , 2019.12.15
Microfluidic three-dimensional cell culture of stem cells for high-throughput analysis, World Journal of Stem Cells , 제11권(집) , 제10호 , PP.803~816 , 2019.10.26
Exosomes: Biogenesis, Composition, Functions, and Their Role in Pre-metastatic Niche Formation, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제24권(집) , 제5호 , PP.689~701 , 2019.09.01
Exosome-based antisense locked nucleic acid delivery for inhibition of type II collagen degradation in chondrocyte, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY , 제74권(집) , PP.126~135 , 2019.06.25
Colorimetric Biosensor using Dual-Amplification of Enzyme-Free Reaction through Universal Hybridization Chain Reaction System, BIOTECHNOLOGY AND BIOENGINEERING , 제116권(집) , 제7호 , PP.1567~1574 , 2019.06.01
Silkworm Storage Protein 1 Inhibits Autophagy-Mediated Apoptosis, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 제20권(집) , 제2호 , 2019.01.14
Bioreducible Polyspermine-Based Gene Carriers for Efficient siRNA Delivery: Effects of PEG Conjugation on Gene Silencing Efficiency, MACROMOLECULAR RESEARCH , 제26권(집) , 제12호 , PP.1135~1142 , 2018.12.10
Detection of exosome miRNAs using molecular beacons for diagnosing prostate cancer, Artificial Cells Nanomedicine and Biotechnology , 제46권(집) , PP.52~63 , 2018.07.22
Exosomes derived from human induced pluripotent stem cells ameliorate the aging of skin fibroblasts, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 제19권(집) , 제6호 , 2018.06.09
Antioxidant potentials of nanoceria synthesized by solution plasma process and its biocompatibility study, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS , 제645권(집) , PP.42~49 , 2018.05.01
Inhibition of apoptosis using exosomes in Chinese hamster ovary cell culture, BIOTECHNOLOGY AND BIOENGINEERING , 제115권(집) , 제5호 , PP.1331~1339 , 2018.05.01
Inhibition of Endoplasmic Reticulum Stress-induced Apoptosis by Silkworm Storage Protein 1, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제23권(집) , 제2호 , PP.194~200 , 2018.04.30
Anti-apoptotic effects of the alpha-helix domain of silkworm storage protein 1, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제22권(집) , 제6호 , PP.671~678 , 2017.12.30
Extracellular Vesicles-Extracellular Vesicle miRNA Detection Using Molecular Beacons, Methods in molecular biology (Clifton, N.J.) , 제1660권(집) , PP.287~294 , 2017.08.31
Anti-oxidative effects of silkworm storage protein 1 in HeLa cell, PROCESS BIOCHEMISTRY , 제55권(집) , PP.199~206 , 2017.04.01
Protein-stabilizing and cell-penetrating properties of alpha-helix domain of 30Kc19 protein, Biotechnology Journal , 제11권(집) , PP.1443~1451 , 2016.08.12
Simultaneous and multiplexed detection of exosome microRNAs using molecular beacons, BIOSENSORS & BIOELECTRONICS , 제86권(집) , PP.202~210 , 2016.07.15
α-Galactosidase delivery using 30Kc19-human serum albumin nanoparticles for effective treatment of Fabry disease, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY , 제100권(집) , 제24호 , PP.10395~10402 , 2016.06.29
Soluble expression and stability enhancement of transcription factors using 30Kc19 cell-penetrating protein, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY , 제100권(집) , PP.3523~3532 , 2016.04.01
분자 비컨을 이용한 살아 있는 세포에서 단일클론항체 경쇄와 중쇄mRNA 검출에 의한 세포주 선별방법, KSBB Journal , 제31권(집) , 제1호 , PP.33~39 , 2016.03.30
Inhibition of Apoptosis in HeLa Cell by Silkworm Storage Protein 1,SP1, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제20권(집) , 제4호 , PP.807~813 , 2015.08.31
In situ single step detection of exosome microRNA using molecularbeacon, BIOMATERIALS , 제54권(집) , PP.116~125 , 2015.07.01
Enhancement of human erythropoietin production in Chinese hamsterovary cells through supplementation of 30Kc19-30Kc6 fusion protein, PROCESS BIOCHEMISTRY , 제50권(집) , 제6호 , PP.973~980 , 2015.05.01
Dimerization of 30Kc19 protein in the presence of amphiphilic moiety and importance of Cys-57 during cell penetration, BIOTECHNOLOGY JOURNAL , 제9권(집) , 제12호 , PP.1582~1593 , 2014.10.29
Stabilization of cellular mitochondrial enzyme complexand sialyltransferase activity through supplementation of 30Kc19protein, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY , 2014.09.06
Identification and characterization of a novel cell-penetrating peptide of 30Kc19 protein derived from Bombyx mori, PROCESS BIOCHEMISTRY , 제49권(집) , 제9호 , PP.1516~1526 , 2014.09.01
Enzyme delivery using the 30Kc19 protein and human serum albumin nanoparticles, BIOMATERIALS , 제35권(집) , 제5호 , PP.1696~1704 , 2014.02.03
Anti-inflammatory effects of silkworm hemolymph on lipopolysaccharide-stimulated macrophages, KOREAN JOURNAL OF CHEMICAL ENGINEERING , 제30권(집) , 제9호 , PP.1784~1789 , 2013.09.01
High-throughput generation of spheroids using magnetic nanoparticles for three-dimensional cell culture, BIOMATERIALS , 제34권(집) , PP.8555~8563 , 2013.08.12
Anti-apoptotic mechanism of silkworm hemolymph in HeLa cell apoptosis, PROCESS BIOCHEMISTRY , 제48권(집) , PP.1375~1380 , 2013.07.21
A protein delivery system using 30Kc19 cell-penetrating protein originating from silkworm, BIOMATERIALS , 제33권(집) , 제35호 , PP.9127~9134 , 2012.09.13
Understanding the mechanistic roles of 30Kc6 gene in apoptosis and specific productivity in antibody-producing Chinese hamster ovary cells, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY , 제94권(집) , PP.1243~1253 , 2012.07.02
Quantum Dot-Fluorescent Protein FRET Probes for Sensing Intracellular pH, ACS NANO , 제6권(집) , 제4호 , PP.2917~2924 , 2012.04.24
Regulation of morphogenesis and neural differentiation of human mesenchymal stem cells using carbon nanotube sheets, INTEGRATIVE BIOLOGY , 제4권(집) , 제6호 , PP.587~594 , 2012.04.02
Enhancement of neurite outgrowth in PC12 cells by iron oxide nanoparticles, BIOMATERIALS , 제32권(집) , 제11호 , PP.2871~2877 , 2011.04.01
Use of molecular beacons to image effects of titanium surface microstructure on beta 1 integrin expression in live osteoblast-like cells, BIOMATERIALS , 제31권(집) , 제30호 , PP.7640~7647 , 2010.10.01
Slow non-specific accumulation of 2'-deoxy and 2'-O-methyl oligonucleotide probes at mitochondria in live cells, NUCLEIC ACIDS RESEARCH , 제38권(집) , 제9호 , 2010.05.01
HuR regulates the expression of stress-sensitive genes and mediates inflammatory response in human umbilical vein endothelial cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , 제107권(집) , 제15호 , PP.6858~6863 , 2010.04.01