인천대학교 생명공학부-나노바이오전공

심민석 증명사진

심민석
고분자공학, 약물 전달
재료과학, 유기화학(1)(2), 고분자공학, 나노의학, 나노바이오실험(2)
032-835-8268
msshim@inu.ac.kr
https://sites.google.com/site/nanobiopolymers/

학 력: 2011.01.14 Case Western Reserve University 공학박사; 2005.02.25 서울대학교 공학사

연구실적: <논문>; Extracellular vesicles with high dual drug loading for safe and efficient combination chemo-phototherapy, Biomaterials Science , 제10권(집) , 제11호 , PP.2817~2830 , 2022.05.31; Piezoelectric Au-decorated ZnO nanorods: Ultrasound-triggered generation of ROS for piezocatalytic cancer therapy, CHEMICAL ENGINEERING JOURNAL , 제435권(집) , 제3호 , PP.135039~ , 2022.05.01; Engineered extracellular vesicle-based sonotheranostics for dual stimuli-sensitive drug release and photoacoustic imaging-guided chemo-sonodynamic cancer therapy, Theranostics , 제12권(집) , 제3호 , PP.1247~1266 , 2022.01.01; Pro-oxidant drug-loaded porphyrinic zirconium metal-organic-frameworks for cancer-specific sonodynamic therapy, COLLOIDS AND SURFACES B-BIOINTERFACES , 제209권(집) , 제1호 , PP.112189~ , 2022.01.01; Beyond hydrophilic polymers in amphiphilic polymer-based self-assembled NanoCarriers: Small hydrophilic carboxylate-capped disulfide drug delivery system and its multifunctionality and multispatial targetability, BIOMATERIALS , 제280권(집) , PP.121307~ , 2022.01.01; Polysorbate-Based Drug Formulations for Brain-Targeted Drug Delivery and Anticancer Therapy, Applied Sciences-Basel , 제11권(집) , 제19호 , 2021.10.08; Metformin and Dichloroacetate Suppress Proliferation of Liver Cancer Cells by Inhibiting mTOR Complex 1, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 제22권(집) , 제18호 , 2021.09.01; Gold nanorods-encapsulated thermosensitive drug carriers for NIR light-responsive anticancer therapy, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY , 제98권(집) , PP.211~216 , 2021.06.25; 3D-Printed Chitosan Composites for Biomedical Applications, Advances in Polymer Science , 제288권(집) , PP.87~116 , 2021.06.18; Safe and Targeted Sonodynamic Cancer Therapy Using Biocompatible Exosome-Based Nanosonosensitizers, ACS Applied Materials & Interfaces , 제13권(집) , 제22호 , PP.25575~25588 , 2021.06.09; Surface Roughness Effects of Pd-loaded Magnetic Microspheres on Reduction Kinetics of Nitroaromatics, BULLETIN OF THE KOREAN CHEMICAL SOCIETY , 제42권(집) , 제6호 , PP.894~899 , 2021.06.01; Efficient and selective cancer therapy using pro-oxidant drug-loaded reactive oxygen species (ROS)-responsive polypeptide micelles, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY , 제95권(집) , PP.101~108 , 2021.03.25; Disrupting the Redox Balance with a Diselenide Drug Delivery System: Synergistic or Antagonistic? , ADVANCED FUNCTIONAL MATERIALS , 제31권(집) , 제6호 , PP.2007275~ , 2021.02.01; Solvent-driven, self-assembled acid-responsive poly(ketalized serine)/siRNA complexes for RNA interference, Biomaterials Science , 제8권(집) , 제23호 , PP.6718~6729 , 2020.12.07; Guanidinium-Incorporated Micelleplexes for Low Toxic and Efficient siRNA Delivery, MACROMOLECULAR RESEARCH , 제28권(집) , 제12호 , PP.1160~1165 , 2020.11.01; Non-ionic polysorbate-based nanoparticles for efficient combination chemo/photothermal/photodynamic therapy, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY , 제88권(집) , PP.260~267 , 2020.08.25; Mitochondria-targeted drug delivery in cancers, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE , 제1866권(집) , 제8호 , PP.165808~ , 2020.08.01; Effects of Decomplexation Rates on Ternary Gene Complex Transfection with alpha-Poly(L-Lysine) or epsilon-Poly(L-Lysine) as a Decomplexation Controller in An Easy-To-Transfect Cell or A Hard-To-Transfect Cell, Pharmaceutics , 제12권(집) , 제6호 , PP.490~ , 2020.05.28; Microfluidic fabrication of fatty alcohol-based microparticles for NIR light-triggered drug release, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY , 제80권(집) , PP.778~783 , 2019.12.25; Controlling complexation/decomplexation and sizes of polymer-based electrostatic pDNA polyplexes is one of the key factors in effective transfection, COLLOIDS AND SURFACES B-BIOINTERFACES , 제184권(집) , PP.110497~ , 2019.12.01; Pro-Oxidant Drug-Loaded Au/ZnO Hybrid Nanoparticles for Cancer-Specific Chemo-Photodynamic Combination Therapy , ACS Biomaterials Science & Engineering , 제5권(집) , 제10호 , PP.5209~5217 , 2019.10.01; ROS-responsive thioether-based nanocarriers for efficient pro-oxidant cancer therapy, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY , 제75권(집) , PP.238~245 , 2019.07.25; Selective Anticancer Therapy Using Pro-Oxidant Drug-Loaded Chitosan-Fucoidan Nanoparticles, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 제20권(집) , 제13호 , PP.3220~ , 2019.07.01; Glycol chitosan-coated near-infrared photosensitizer-encapsulated gold nanocages for glioblastoma phototherapy, Nanomedicine-Nanotechnology Biology and Medicine , 제18권(집) , PP.315~325 , 2019.06.01; Targeted siRNA delivery using aptamer-siRNA chimeras and aptamer-conjugated nanoparticles, Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology , 제11권(집) , 제e1543호 , 2019.05.01; Bioreducible polyspermine-based gene carriers for efficient siRNA delivery: Effects of PEG conjugation on gene silencing efficiency, MACROMOLECULAR RESEARCH , 제26권(집) , 제12호 , PP.1135~1142 , 2018.12.01; Microfluidic fabrication of biocompatible poly(N-vinylcaprolactam)-based microcarriers for modulated thermo-responsive drug release, COLLOIDS AND SURFACES B-BIOINTERFACES , 제172권(집) , PP.380~386 , 2018.12.01; Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives, Acta Pharmaceutica Sinica B , 제8권(집) , PP.862~880 , 2018.10.01; Hydroxyapatite from Cuttlefish Bone: Isolation, Characterizations, and Applications, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING , 제23권(집) , PP.383~393 , 2018.09.13; Cancer-targeted photothermal therapy using aptamer-conjugated gold nanoparticles, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY , 제67권(집) , PP.429~436 , 2018.09.01; Photo-triggered antibacterial and anticancer activities of zinc oxide nanoparticles, Journal of Materials Chemistry B , 제6권(집) , 제30호 , PP.4852~4871 , 2018.08.14; Cancer-specific pro-oxidant therapy using low-toxic polypeptide micelles encapsulating piperlongumine, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY , 제63권(집) , PP.57~64 , 2018.07.25; Studies on three-phase three-dimensional hybrid electrochemical reactor for treating textile effluent, DESALINATION AND WATER TREATMENT , 제116권(집) , PP.242~250 , 2018.06.30; Preparation, characterization and biological applications of biosynthesized silver nanoparticles with chitosan-fucoidan coating, MOLECULES , 제23권(집) , 제6호 , PP.1429~ , 2018.06.12; Fabrication of dual stimuli-responsive multicompartmental drug carriers for tumor-selective drug release , LAB ON A CHIP , 제18권(집) , 제4호 , PP.754~764 , 2018.03.07; Bioreducible polymer micelles based on acid-degradable poly(ethylene glycol)-poly(amino ketal) enhance the stromal cell-derived factor-1α gene transfection efficacy and therapeutic angiogenesis of human adipose-derived stem cells, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 제19권(집) , 제2호 , PP.529~ , 2018.02.10; Chitosan as a vehicle for growth factor delivery: Various preparations and their applications in bone tissue regeneration, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 제104권(집) , PP.1383~1397 , 2017.09.19; Marine fish proteins and peptides for cosmeceuticals: A review, Marine Drugs , 제15권(집) , 제5호 , PP.143~ , 2017.05.19; Antimicrobial and anticancer activities of porous chitosan-alginate biosynthesized silver nanoparticles, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 제98권(집) , PP.515~525 , 2017.05.01; Antimicrobial, antioxidant, and anticancer activitiesof biosynthesized silver nanoparticles using marinealgae Ecklonia cava, Nanomaterials , 제6권(집) , 제12호 , PP.235~ , 2016.12.06; Preparation of piperlongumine-loaded chitosannanoparticles for safe and efficient cancer therapy, RSC Advances , 제6권(집) , 제83호 , PP.79307~79316 , 2016.08.22; Combination of nano-hydroxyapatite with stem cells for bone tissue engineering, JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY , 제16권(집) , 제9호 , PP.8881~8894 , 2016.08.02; Targeted and effective photodynamic therapy for cancer using functionalized nanomaterials, Acta Pharmaceutica Sinica B , 제6권(집) , 제4호 , PP.297~307 , 2016.07.18; Microfluidic Synthesis of pH-SensitiveMulticompartmental Microparticles for MultimodulatedDrug Release, Small , 제12권(집) , 제25호 , PP.3463~3470 , 2016.07.06; "Combo" nanomedicine: Co-delivery of multi-modal therapeutics forefficient, targeted, and safe cancer therapy, ADVANCED DRUG DELIVERY REVIEWS , 제98권(집) , PP.3~18 , 2016.03.01; Preparation and characterization of chitosan-natural nanohydroxyapatite-fucoidan nanocomposites for bone tissue engineering, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , 제93권(집) , PP.1479~1487 , 2016.02.26; Seaweed Polysaccharide-Based Nanoparticles: Preparation and Applications for Drug Delivery, POLYMERS , 제8권(집) , 제2호 , PP.30~ , 2016.01.26; Engineered photo-responsive materials for near-infrared-triggered drug delivery, JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY , 제31권(집) , PP.15~25 , 2015.11.25; Stimuli-Responsive Materials for Controlled Release of Theranostic Agents, ADVANCED FUNCTIONAL MATERIALS , 제24권(집) , 제27호 , PP.4206~4220 , 2014.07.16; Nano-enabled drug delivery: A research profile, NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE , 제10권(집) , 제5호 , PP.889~896 , 2014.07.01; Synthetically designed peptide-based biomaterials with stimuli-responsive and membrane-active properties for biomedical applications, JOURNAL OF MATERIALS CHEMISTRY B , 제2권(집) , 제6호 , PP.595~615 , 2014.02.14; Nanoparticles with dual responses to oxidative stress and reduced pH for drug release and anti-inflammatory applications, ACS Nano , 제8권(집) , 제2호 , PP.1213~1221 , 2014.01.03; Stimuli-responsive siRNA carriers for efficient gene silencing in tumors via systemic delivery, BIOMATERIALS SCIENCE , 제2권(집) , 제1호 , PP.35~40 , 2014.01.01; A Reactive Oxygen Species (ROS)-Responsive Polymer for Safe, Efficient, and Targeted Gene Delivery in Cancer Cells, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION , 제52권(집) , 제27호 , PP.6926~6929 , 2013.02.28; A bioreducible polymer for efficient delivery of fas-silencing siRNA into stem cell spheroids and enhanced therapeutic angiogenesis, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION , 제51권(집) , 제47호 , PP.11899~11903 , 2012.11.19; Ketalized poly(amino ester) for stimuli-responsive and biocompatible gene delivery, Polymer Chemistry , 제3권(집) , 제9호 , PP.2570~2577 , 2012.09.01; Stimuli-responsive polymers and nanomaterials for gene delivery and imaging applications, ADVANCED DRUG DELIVERY REVIEWS , 제64권(집) , 제11호 , PP.1046~1059 , 2012.08.01; siRNA as a conventional drug in the clinic? Challenges and current technologies, Drug Discovery Today: Technologies , 제9권(집) , 제2호 , PP.167~173 , 2012.06.01; Dual mode polyspermine with tunable degradability for plasmid DNA and siRNA delivery, BIOMATERIALS , 제32권(집) , 제16호 , PP.4009~4020 , 2011.06.01; Efficient and targeted delivery of siRNA in vivo, FEBS JOURNAL , 제277권(집) , 제23호 , PP.4814~4827 , 2010.12.01; Dynamics of Nucleic Acid/Cationic Polymer Complexation and Disassembly Under Biologically Simulated Conditions Using In Situ Atomic Force Microscopy, MICROSCOPY RESEARCH AND TECHNIQUE , 제73권(집) , 제9호 , PP.845~856 , 2010.09.01; Combined Multimodal Optical Imaging and Targeted Gene Silencing Using Stimuli-Transforming Nanotheragnostics, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , 제132권(집) , 제24호 , PP.8316~8324 , 2010.06.01; Acid-transforming polypeptide micelles for targeted nonviral gene delivery, BIOMATERIALS , 제31권(집) , 제12호 , PP.3404~3413 , 2010.04.01; <저서>; Bone Response to Dental Implant Materials, Woodhead Publishing , 2016.10.28