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제목 Professor Kyobum Kim Developed Scar-less Skin Regeneration Technology
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작성일 2019.05.03 13:10:13 조회수 83
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simple The research result is issued in Acta Biomaterialia, suggesting to be the future baseline data for biological tissue engineering platform development.
newsDay 2019.04.29

INU Professor Kyobum Kim (Department of Life Biological Engineering) published latest technology about skin regeneration on Acta Biomaterialia (impact factor: 6.38). The paper proves exogenous delivery of therapeutic growth factors(GF) and using coacervates(Coa), reduces scar formation during physiological wound healing.  
 
This research result indicates the exogenous administration of dual GF through Coa enhances the proliferation and migration of skin-related cells. By directly injecting the dual GF Coa around the damaged skin, the skin could be regenerated without scar formation. 

The study is proved by rat experiment. After injecting the dual GF Coa into the edge of damaged skin of the rat, wound closure and skin regeneration was accelerated after three weeks. 
 
Professor Kim commented that his study was the succession of patch-type medication for skin tissue regeneration that was developed around 2017 in his lab. He mentioned that this research on skin regeneration will be the necessary baseline data for biological tissue engineering platform development in medical purpose. Professor Kim stressed the research result again that scar generation could be effectively restrained through infecting only once. 
 
For the paper, INU student Uiseon Park (Graduate school of Nano-bio Engineering) participated as the lead author, Cornell University and Dankook University internationally cooperated, and National Research Foundation of Korea's Rising Researcher Project funded the research.   

 (Name of the Article: Coacervate-mediated Exogenous Growth Factor Delivery for Scar-less Skin Regeneration)
 (This news partially extracted the Abstract section in Acta Biomaterialia
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